Regulation of β-Cell Function by Lipids
Dr. Amy Tse
A decrease in the ability of β cells to secrete insulin when challenged by an elevation in plasma glucose is a hallmark of type 2 diabetes. This project focuses on understanding the influence of two lipids: arachidonic acid and cholesterol on Ca2+ signaling and exocytosis in pancreatic β cells.
Time line: 2006 to present
Stage of Project: discovery