Regulation of β-Cell Function by Lipids

Dr. Amy Tse

Amy TseRodent study

A decrease in the ability of β cells to secrete insulin when challenged by an elevation in plasma glucose is a hallmark of type 2 diabetes. This project focuses on understanding the influence of two lipids: arachidonic acid and cholesterol on Ca2+ signaling and exocytosis in pancreatic β cells. 

Time line: 2006 to present

Stage of Project: discovery