Raj Padwal, MD
Office: 2F1.26 Walter C. Mackenzie Health Sciences Centre
Mail: 8440-112 Street Edmonton, Alberta T6G 2B7
Associate Professor, Department of Medicine, University of Alberta
Director, Hypertension Clinic, University of Alberta
I have a background in general internal medicine, clinical pharmacology and clinical epidemiology. I am an academic internist and a health services researcher with an interest in cardiovascular risk management. Specific areas of interest include primarily bariatric (obesity) care and hypertension addressing care-gaps.
I am a physician, epidemiologist and health services researcher, with expertise in clinical pharmacology, general internal medicine and clinical epidemiology. I specialize in the care of adult patients with complex, multisystem disease, including (but not limited to) hypertension and other chronic cardiovascular diseases. I am the Director of the University of Alberta Hypertension Clinic and the Co-Chair of the Canadian Hypertension Education Program Recommendations Task Force. A large part of my research focuses on bariatric (obesity) care delivery in Canada.
Current Research Activities
a. Leading a 500-patient CIHR-funded prospective observational study (APPLES) examining the clinical, economic and humanistic (satisfaction, health-related quality of life) ramifications of protracted wait times for bariatric surgery. This study involves a comparison of medically-treated, surgically-treated and wait-listed patients.
b. Leading a CIHR-funded study that aims to identify potential prioritization indicators for bariatric surgery (OASIS study).
c. Leading a CIHR-funded RCT examining the effectiveness of community-based education for obesity in reducing weight and preparing patients for bariatric intervention (EVOLUTION study).
d. Coinvestigator in an RCT examining the efficacy of pharmacist-led case management in improving blood pressure and lipid control in patients who have experienced a stroke or TIA.
e. a Site Lead for industry-sponsored clinical trials in obesity and hypertension.
Other Activities and Affiliations
Co-Chair, Canadian Hypertension Recommendations Task Force
CIHR Health Services Research Panels 1 and 2
Padwal R, Klarenbach S, Wiebe N, Birch D, Karmali S, Manns B, Hazel M, Sharma AM, Tonelli M. Bariatric surgery: a systematic review and network meta-analysis of randomized trials. Obes Rev 2011;12:602-21.
Padwal RS, Gabr RQ, Sharma AM, Langkaas L, Birch DW, Karmali S, Brocks DR. The effect of gastric bypass surgery on the absorption and bioavailability of metformin. Diabetes Care. 2011;34:1295-300.
Oreopoulos A, Ezekowitz J, McAlister FA, Kalantar-Zadeh K, Fonarow GC, Norris CM, Johnson JA, Padwal RS*. Association between direct measures of body composition and prognostic factors in chronic heart failure. Mayo Clin Proc 2010; 85:609-17.
Padwal RS*, Majumdar SR. New Drug Classes: Drug treatments for obesity: orlistat, sibutramine, and rimonabant. Lancet 2007; 369:71-7.
Padwal R*, Sharma AM. Treating severe obesity: morbid weights and morbid waits. CMAJ 2009;181(11) 777-78.
Padwal RS*, Majumdar SR, Klarenbach S, Birch DW, Karmali S, McCargar L, Fassbender K, Sharma AM. The Alberta population-based prospective evaluation of the quality of life outcomes and economic impact of bariatric surgery (APPLES) study: background, design, and rationale. BMC Health Serv Res 2010; 0:284.
Oreopoulos A, Kalantar-Zadeh K, McAlister FA, Ezekowitz J, Fonarow GC, Johnson JA, Norris CM, Padwal RS*. Comparison of direct body composition methods in patients with chronic heart failure. J Card Fail 2010;16:867-72.
Padwal RS*, Sharma AM. Prevention of cardiovascular disease: obesity, diabetes and the metabolic syndrome. Can J Cardiol 2010; 26(Suppl C): 18C-20C.
Padwal RS*, Pajewsky NM, Allison DB, Sharma AM. The Edmonton Obesity Staging System for predicting mortality in an overweight and obese population-representative cohort. CMAJ 2011. 183;E1059-66.